CARDIOVASCULAR MEDICINE Assessment of myocardial perfusion abnormalities by intravenous myocardial contrast echocardiography with harmonic power Doppler imaging: comparison with positron emission tomography
نویسندگان
چکیده
Background: Intravenous myocardial contrast echocardiography with harmonic power Doppler imaging (HPDI) enables assessment of myocardial perfusion. Its accuracy in comparison with positron emission tomography (PET), which is one of the most reliable clinical gold standards for myocardial perfusion, remains to be determined. Objective: To assess the ability of HPDI to identify myocardial perfusion abnormalities, using PET as a gold standard. Methods: 23 patients with myocardial infarction underwent HPDI. Images were obtained from the apical two and four chamber views at pulsing intervals of one to eight cardiac cycles with continuous infusion of Levovist (Schering, Germany). PET was done within two weeks of HPDI. The left ventricle was divided into 12 segments and myocardial opacification by HPDI and uptake of NH3 by PET in each segment was graded as normal, mildly reduced, or severely reduced. Results: Of the 276 segments examined, adequate image quality was obtained in 226 (82%) by HPDI; 50 segments were excluded because of inadequate image quality. There were more exclusions in the basal segments than in the mid or apical segments (p < 0.0001). Of the 226 segments analysed, overall concordance between HPDI and PET was 82% (κ = 0.70). In the apex, more segments were overestimated by HPDI than were underestimated (χ = 6.25, p = 0.012). Conclusions: HPDI and PET gave similar results in the assessment of myocardial perfusion abnormalities. However, poor image quality in the basal segments and overestimation of perfusion in the apical segments are current limitations of HPDI.
منابع مشابه
Prediction of Changes in Left Ventricular Ejection Fraction after Off-Pump Coronary Artery Bypass Grafting Surgery by Myocardial Perfusion Single-Photon Emission Computed Tomography
Introduction: Left ventricular ejection fraction (LVEF) is considered to be the single most important prognostic factor in patients with previous myocardial infarction. LVEF is not improved in all patients after coronary artery bypass grafting (CABG). This study aimed to assess the possibility of prediction of LVEF changes after CABG using myocardial perfusion gated signle photon emission compu...
متن کاملAdvances in Cardiovascular Imaging Noninvasive Assessment of Myocardial Perfusion
Noninvasive assessment of myocardial perfusion is important in the diagnosis and risk stratification of patients with known or suspected coronary artery disease (CAD). Although single-photon emission computed tomography (SPECT) is most commonly used, multiple modalities including myocardial contrast echocardiography (MCE), positron emission tomography (PET), cardiac MRI (CMR), and cardiac compu...
متن کاملAssessment of myocardial viability.
600 Assessment of resting perfusion with myocardial contrast echocardiography: a comparison with tecnetium single-photon emission computed tomography and dobutamine echocardiography C. Palagi r, G. Mengozzi 1, L. Rondinini 1, MG. Delle Donne 1, p. Caravelli 1, L. Papi 1, E. De Felice 1, D. Volterrani 2, CR. Bellina e, M. Mariani Cardio-Thoracic Dept., Cisanello Hospital, Pisa, Italy 1, Oncology...
متن کاملEffect of power Doppler and digital subtraction techniques on the comparison of myocardial contrast echocardiography with SPECT.
OBJECTIVE To compare the accuracy and feasibility of harmonic power Doppler and digitally subtracted colour coded grey scale imaging for the assessment of perfusion defect severity by single photon emission computed tomography (SPECT) in an unselected group of patients. DESIGN Cohort study. SETTING Regional cardiothoracic unit. PATIENTS 49 patients (mean (SD) age 61 (11) years; 27 women, ...
متن کاملTricky image of exuberant accessory mitral valve tissue with partial interchordal space obliteration.
volume-rate three-dimensional stress echocardiography to assess inducible myocardial ischemia: a feasibility study. J Am Soc Echocardiogr 2010;23:628–35. 24. Nemes A, Geleijnse ML, Krenning BJ, Soliman OI, Anwar AM, Vletter WB et al. Usefulness of ultrasound contrast agent to improve image quality during real-time three-dimensional stress echocardiography. Am J Cardiol 2007;99:275–8. 25. Abdelm...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2002